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2026-09-01 国立長寿医療研究センター

国立長寿医療研究センターの研究グループは、加齢による脳の萎縮があっても認知機能を維持する特性「認知予備能」を測定する認知予備能指数質問票(CRIq)の日本語版(CRIq-J)と短縮版(sCRIq-J)を作成し、その信頼性・妥当性を検証した。CRIqは教育年数だけでなく、職業や余暇活動も含めて認知予備能を包括的に評価する指標である。研究では、原著者の許諾を得て翻訳・逆翻訳を行い、日本の高齢者の社会文化的背景に適合する日本語版を作成した。その後、地域在住高齢者3,567人を対象にスコアと認知機能との関連を調査した結果、CRIq-JおよびsCRIq-Jのスコアは認知機能と有意な正の関連を示した。また、CRIq-Jのスコアが高いほど全般的認知機能障害との関連が低かった。今後は、これらのスコアが将来の要介護や認知症発症を予測できるかを検証し、認知予備能の評価・研究への活用を目指す。

「脳の蓄え」を可視化する
図 研究結果の概要

<関連情報>

認知予備能指数質問票の日本語翻訳研究 The Japanese Translation Study of the Cognitive Reserve Index Questionnaire

Osamu Katayama, Ryo Yamaguchi, Daiki Yamagiwa, Shoma Akaida, Takahiro Shimoda, Chika Nakajima, Ayuka Kawakami, Kenji Harada, Sho Nakakubo, Fumio Sakimoto, Soichiro Matsuda, …
Geriatrics & Gerontology International  Published: 17 August 2026
DOI:https://doi.org/10.1111/ggi.70803

ABSTRACT

Background
The cognitive reserve index questionnaire (CRIq) is widely used to quantify cognitive reserve (CR), but a validated Japanese version is lacking. This study aimed to translate and culturally adapt the CRIq and its short version (s-CRIq) into Japanese (CRIq-J and sCRIq-J) and to evaluate their reliability and criterion-related validity.

Methods
Following international guidelines for cultural adaptation and translation, we translated and culturally adapted the CRIq and s-CRIq into Japanese. The study participants were 3567 community-dwelling Japanese older adults from a large-scale cohort. Global cognitive performance was assessed with the composite score of the National Center for Geriatrics and Gerontology–Functional Assessment Tool and global cognitive impairment (GCI) was defined as a mini-mental state examination score ≤ 23. Internal consistency was assessed using Cronbach’s alpha. Multiple and logistic regression analyses were performed to examine associations between CRIq-J and sCRIq-J total scores and global cognitive performance, including GCI.

Results
Cronbach’s alpha coefficients were 0.58 for the CRIq-J and 0.48 for the sCRIq-J, reflecting the multidimensional nature of life-course experiences. After adjusting for age and sex, higher scores on both the CRIq-J (β = 0.21, 95% CI: 0.18–0.24, p < 0.001) and sCRIq-J (β = 0.21, 95% CI: 0.17–0.25, p < 0.001) were significantly associated with superior cognitive performance. Furthermore, higher CRI levels were associated with a significantly lower likelihood of GCI.

Conclusions
The CRIq-J and sCRIq-J demonstrated acceptable reliability and robust criterion-related validity in a Japanese population. These standardized tools represent a significant milestone for future CR research and the development of dementia prevention strategies in Japan.

医療・健康
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