家畜化 羊飼育の遺伝的ボトルネック(Domestication: Genetic bottleneck of sheep husbandry)

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2024-04-15 ミュンヘン大学(LMU)

アナトリアのアシュクリ・ヒュユク遺跡での研究により、現代のユーラシアの羊は、初期の家畜化時には遺伝的多様性が急速に減少したという以前の仮定が否定されました。約1,000年間にわたる羊の飼育と繁殖に人間が介入しても、ミトコンドリアゲノムの多様性が高いことが示されました。この発見は、新石器時代後期に起こった後の「ボトルネック」によって生じたものと考えられています。

<関連情報>

新石器時代以前の中央アナトリアの古代ミトゲノムとヒツジ(Ovis aries)における新石器時代後期のボトルネックの影響 Ancient mitogenomes from Pre-Pottery Neolithic Central Anatolia and the effects of a Late Neolithic bottleneck in sheep (Ovis aries)

EDSON SANDOVAL-CASTELLANOS , ANDREW J. HARE , AUDREY T. LIN , EVANGELOS A. DIMOPOULOS , […], AND JORIS PETERS

Science Advances  Published:12 Apr 2024

DOI:https://doi.org/10.1126/sciadv.adj0954

Abstract

Occupied between ~10,300 and 9300 years ago, the Pre-Pottery Neolithic site of Aşıklı Höyük in Central Anatolia went through early phases of sheep domestication. Analysis of 629 mitochondrial genomes from this and numerous sites in Anatolia, southwest Asia, Europe, and Africa produced a phylogenetic tree with excessive coalescences (nodes) around the Neolithic, a potential signature of a domestication bottleneck. This is consistent with archeological evidence of sheep management at Aşıklı Höyük which transitioned from residential stabling to open pasturing over a millennium of site occupation. However, unexpectedly, we detected high genetic diversity throughout Aşıklı Höyük’s occupation rather than a bottleneck. Instead, we detected a tenfold demographic bottleneck later in the Neolithic, which caused the fixation of mitochondrial haplogroup B in southwestern Anatolia. The mitochondrial genetic makeup that emerged was carried from the core region of early Neolithic sheep management into Europe and dominates the matrilineal diversity of both its ancient and the billion-strong modern sheep populations.

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