小児の心停止発生における救急隊到着前の実態からひも解くAEDパッド装着と良好な神経学的転帰との関連性

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2026-08-03 国立循環器病研究センター,大阪大学

国立循環器病研究センターと大阪大学の研究チームは、総務省消防庁の全国院外心停止登録データを用い、2021~2023年に発生した小児院外心停止3,352例を対象に、救急隊到着前のAED(自動体外式除細動器)パッド装着の実態と転帰を解析した。その結果、AEDパッドが救急隊到着前に装着されていたのは全体の5.5%にとどまり、学校での発生例や居合わせた人による心肺蘇生(CPR)が実施された例で装着率が高かった。一方、家庭内や夜間、乳児・幼児では装着率が低く、救命体制の課題が明らかとなった。また、AEDパッド装着群では良好な神経学的転帰(脳機能が保たれた状態)の割合が非装着群より有意に高く、多変量解析でも良好な転帰との関連が認められた(調整後オッズ比3.11)。特に心室細動症例ではその関連がより顕著であった。本研究は、小児心停止におけるAEDの早期使用の重要性を示すとともに、学校だけでなく運動施設や商業施設などでのAED配置や救命教育の充実が必要であることを示している。

小児の心停止発生における救急隊到着前の実態からひも解くAEDパッド装着と良好な神経学的転帰との関連性
※画像は生成AIを使用して作成。

<関連情報>

小児院外心停止における救急隊到着前の自動体外式除細動器(AED)パッド装着 Automated External Defibrillator Pad Application Before EMS Arrival in Pediatric Out-of-Hospital Cardiac Arrest

Aoi Yamaguchi, BS; Aya Fukuzawa, PhD; Masaya Atsuta, BS:et al
JAMA Network Open  Published:July 24, 2026
DOI:10.1001/jamanetworkopen.2026.25069

Key Points

Question What is the current rate of automated external defibrillator (AED) pad application before emergency medical service (EMS) arrival in pediatric out-of-hospital cardiac arrest (OHCA), and is AED pad application associated with neurological outcomes?

Findings In this cohort study of 3352 pediatric patients with OHCA in Japan, AED pads were applied before EMS arrival in 5.5% of pediatric OHCAs, and AED pad application was provided more often at school and when bystander CPR was provided, but less often at home, at night, and among infants. AED pad application was associated with higher 1-month survival with a favorable neurological outcome after OHCA.

Meaning These findings could serve as foundational data for formulating strategies to further increase AED pad application for pediatric patients with OHCA.

Abstract

Importance The current rate of automated external defibrillator (AED) pad application before emergency medical service (EMS) arrival in pediatric out-of-hospital cardiac arrest (OHCA) in Japan has not been sufficiently investigated.

Objective To describe the current rate of AED pad application and evaluate factors associated with AED pad application as well as factors associated with survival in pediatric patients with OHCA.

Design, Setting, and Participants This was a nationwide, prospective, population-based cohort study using data from the All-Japan Utstein Registry between 2021 and 2023. Pediatric patients with OHCA aged 0 to 17 years in whom resuscitation was attempted before EMS arrival were included. Data analyses were conducted from January to May 2026.

Exposure OHCA stratified by age (infants [<1 year], younger children [1-4 years], older children [5-12 years], and adolescents [13-17 years]).

Main Outcomes and Measures The outcome measures were the application of AED pads before EMS arrival as well as 1-month survival with a favorable neurological outcome, defined as a cerebral performance category scale of 1 or 2. Multivariable logistic regression analyses were performed to estimate adjusted odds ratios (aORs) and 95% CIs for factors associated with each outcome.

Results A total of 3352 pediatric patients with OHCA were analyzed. The median (IQR) age was 3 (1-4) years, 1983 patients (59.2%) were male, and 185 patients (5.5%) received AED pad application before EMS arrival. Arrests among infants (aOR, 0.28; 95% CI, 0.13-0.47) and younger children (aOR, 0.22; 95% CI, 0.10-0.49) vs adolescents, arrests occurring at home vs another public area (aOR, 0.06; 95% CI, 0.03-0.11), and arrests occurring at nighttime vs daytime (aOR, 0.52; 95% CI, 0.33-0.82) were significantly associated with a reduced probability of AED pad application before EMS arrival. In contrast, arrests occurring at school vs another public area (aOR, 6.74; 95% CI, 3.73-12.21) and receipt of bystander CPR (aOR, 28.69; 95% CI, 12.91-63.75) were associated with an increased probability of AED pad application before EMS arrival. Favorable neurological outcome was significantly higher in the AED pad application group than in the non–AED pad application group (aOR, 3.11; 95% CI, 1.30-7.44). Ventricular fibrillation as first documented rhythm had a large magnitude of association with increased favorable neurological outcome (aOR, 27.49; 95% CI, 13.95-54.19).

Conclusions and Relevance In this cohort study from Japan, approximately 5% of pediatric patients with OHCA received AED pad application before EMS arrival, and AED pad application was associated with higher odds of 1-month survival with a favorable neurological outcome. Further efforts are needed to increase AED access and use in public places where children gather, including schools.

医療・健康
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