犬の歩幅は認知機能低下の指標となる(Stride Length is Marker for Cognitive Decline in Dogs)

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2026-06-25 ノースカロライナ州立大学(NC State)

米国ノースカロライナ州立大学の研究チームは、高齢犬の歩行パターンを解析することで、認知機能低下を早期に検出できる可能性を示した。研究では、高齢犬の歩幅、歩行速度、歩行周期、左右の対称性などを詳細に測定し、認知機能評価の結果と比較した。その結果、認知機能が低下した犬では歩行が遅くなり、歩幅や歩行リズムの変化、歩行の安定性低下が認められ、歩行特性が認知機能低下の程度と関連することが明らかになった。これらの変化は、従来の行動観察だけでは把握しにくい初期段階でも検出できる可能性があり、非侵襲的な認知症評価法として有望である。犬の認知機能障害はヒトのアルツハイマー病と類似した病態を示すことから、本研究は伴侶動物の健康管理だけでなく、ヒトの認知症の早期診断や病態解明にも貢献することが期待される。今後は、より多くの犬種や長期追跡調査を通じて診断精度の向上を目指す。

<関連情報>

高齢犬における前肢の歩幅は認知機能障害と関連している Thoracic limb stride length is associated with cognitive impairment in aging dogs

Shaghayegh Rafatpanah Baigi,Akiya Stywall,Chin Chieh Yang,Alejandra Mondino,Gilad Fefer,Wojciech K. Panek,Katherine E. Simon,Beth C. Case,Margaret E. Gruen,Natasha J. Olby
Frontiers in Veterinary Science  Published:25 June 2026
DOI:https://doi.org/10.3389/fvets.2026.1814017

犬の歩幅は認知機能低下の指標となる(Stride Length is Marker for Cognitive Decline in Dogs)

Abstract

Introduction:

Changes in stride length have been linked to cognitive impairment in humans with dementia. In aging dogs, cognitive decline is accompanied by slower gait speed. However, the relationship between stride length and cognitive decline has not been investigated. This study examined whether height-adjusted stride length is associated with owner-reported cognitive impairment in aging companion dogs.

Methods:

Data were collected from a cohort of client-owned senior and geriatric pet dogs, enrolled in the Longitudinal Study of Canine Neuroaging. On-leash gait was recorded on a standardized 5 m walkway, and stride lengths were derived from video analysis and normalized to withers height. Cognitive function was assessed using the Canine Dementia Scale (CADES), and pain was evaluated using the Canine Brief Pain Inventory (CBPI). Associations between height-adjusted stride length, age, CADES, and CBPI scores were examined using linear mixed-effects models.

Results:

Eighty-eight dogs were enrolled. Height adjustment reduced the influence of body size on stride length. Thoracic limb height-adjusted stride length decreased significantly with age, whereas pelvic limb stride showed no significant age-related association. Although CADES scores increased with age, their association with stride length persisted after adjustment for age and pain, while age alone was not a significant predictor in the multivariable model. Intra-observer and interobserver reliability for stride length measurements were excellent.

Conclusion:

These findings support the use of thoracic limb stride length as an objective, scalable functional mobility measure that reflects changes associated with cognitive decline and may be a useful tool for research and clinical monitoring of aging in dogs.

医療・健康
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