2026-09-22 ローレンスリバモア国立研究所(LLNL)
The scaffolds hold microorganisms in place, providing an alternative to the traditional liquid-based reaction.
＜関連情報＞
- https://www.llnl.gov/article/54996/3d-printed-solid-state-bioreactor-converts-methane-waste-useful-chemicals
- https://www.nature.com/articles/s41598-026-54237-1
気体廃液流からの効率的なエネルギー回収のための固体バイオリアクター Solid-state bioreactors for efficient energy recovery from gaseous waste streams
Samantha Ruelas, Hawi B. Gemeda, Nathan C. Ellebracht, Joshua R. DeOtte, Jennifer M. Knipe, Natalie A. Hwee, Ellsbeth Webb, Michael T. Guarnieri, Calvin A. Henard, Xumeng Ge, Eric B. Duoss, Sarah E. Baker & Fang Qian
Scientific Reports Published:22 July 2026
DOI:https://doi.org/10.1038/s41598-026-54237-1 Early provide
Abstract
Energy recovery from gas-phase waste streams is essential for reducing environmental impact, promoting sustainable industrial practices, and increasing profit margins. Compared to thermochemical pathways, biocatalytic conversions offer a compelling alternative due to their mild operating conditions and high specificity. However, conventional systems are hindered by slow gas-to-liquid mass transfer, resulting in high energy consumption and low productivity. Here, we demonstrate a new solid-state bioreactor (SSB) technology through a case study of methane-to-succinate conversion using methanotrophs. SSBs immobilize high densities of methanotrophs within gas-permeable, 3D-printed geometries that operate under gas-phase and static conditions. These reactors exhibit a 1–2 order of magnitude increase in biocatalytic performance compared to traditional liquid-phase reactors. Computational models of the SSB are developed and benchmarked against conventional stirred-tank reactor models to highlight design advantages.
