2026-09-15 理化学研究所
図1 マウス大脳皮質の大規模神経活動データセット
＜関連情報＞
- https://www.riken.jp/press/2026/20260915_1/index.html
- https://www.nature.com/articles/s41597-026-08202-2
覚醒時、睡眠時、麻酔時におけるマウス皮質の複数領域単一細胞カルシウムイメージングデータセット Multi-area single-cell calcium imaging dataset of the mouse cortex across wakefulness, sleep, and anesthesia
Ikumi Oomoto,Daiki Kiyooka,Masafumi Oizumi & Masanori Murayama
Scientific Data Published:10 September 2026
DOI:https://doi.org/10.1038/s41597-026-08202-2 Early Provide
Abstract
We present a reusable dataset of neuronal population activity from multiple cortical areas, recorded from layers 2/3 of the mouse cortex at single-cell resolution during wakefulness, natural sleep (including NREM and REM sleep), and isoflurane anesthesia. Using wide-field two-photon microscopy, we recorded approximately 4,000 to 10,000 neurons per session at 7.65 Hz and provided the spatial coordinates of individual neurons. The repository provides both processed datasets and the corresponding raw imaging movies (TIFF) and electrophysiological recordings (MATLAB format). Processed data are distributed in MATLAB format and include ΔF/F fluorescence signals, deconvolved spike estimates, Gaussian-smoothed spike estimates, behavioral state annotations, and metadata. This dataset supports reuse in studies of cortical population dynamics, brain-state-dependent activity, and spatially distributed neuronal organization. It should also be useful for method development, benchmarking, and comparative analyses of large-scale neuronal activity across physiological and pharmacological brain states.
